Some products have ingredients that could affect your heart rate or blood pressure. Different individuals may respond to medication in different ways. Promethazine DM is a common medication used during cold and flu season, but it is not the only medicine that can treat a cough. Precautions against aspiration must be taken, especially in infants and small children. Verywell Health's content is for informational and educational purposes only. C 16H 19BrN 2C 4H 4O 4 M.W. Talk to your doctor if you are using marijuana (cannabis). MAOIs can be used for depression, mood disorders, or Parkinson's syndrome. This means that any drug that impacts CYP2D6 enzymes might not be cleared as quickly. Make a copy of your Promethazine DM prescription, and if possible, keep your medication in its original container from your pharmacy with your name on the label. You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood. To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. Do not drive, use machinery, or do anything that needs alertness or clear vision until you can do it safely. Dosage of drugs is not considered in the study. Antihistamines relieve watery eyes, itchy eyes/nose/throat, runny nose, and sneezing.Cough-and-cold products have not been shown to be safe or effective in children younger than 6 years. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Interaction more likely in certain predisposed pts. Bromfed DM doesnt contain any opioids, including codeine. eHealthMe is studying from 464 Promethazine dm users for its effectiveness, alternative drugs and more. This document does not contain all possible drug interactions. 10 mg. Inactive Ingredients: sucrose, glycerin, ethyl alcohol, propylene glycol, methylparaben, citric acid, sodium citrate dihydrate, sodium benzoate, FD&C Red No. PMID:31335081, Gillman PK. We compare the side effects and drug effectiveness of Bromfed-dm and Promethazine. How Can I Stay Healthy While Taking Promethazine DM? Oxygen, intravenous fluids, and other supportive measures should be employed as indicated. If you forget your medicine at home and are traveling internationally, you might be able to purchase Promethazine DM at your destination, depending on local laws and rules. . Other drugs that have the same active ingredients (e.g. 7 Can you take bromfed DM if you have asthma? System: Epigastric discomfort, anorexia, nausea, vomiting, diarrhea, constipation. Management of chronic refractory cough in adults. WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health. Some products that may interact with this drug are: antihistamines applied to the skin (such as diphenhydramine cream, ointment, spray), ketoconazole, levoketoconazole, rolapitant. Tell your doctor or pharmacist if you are taking other products that cause drowsiness such as opioid pain or cough relievers (such as codeine, hydrocodone), alcohol, marijuana (cannabis), drugs for sleep or anxiety (such as alprazolam, lorazepam, zolpidem), muscle relaxants (such as carisoprodol, cyclobenzaprine), or other antihistamines (such as cetirizine, diphenhydramine). . Patients should be warned about engaging in activities requiring mental alertness, such as driving a car or operating dangerous machinery. These may be symptoms of a serious medical problem and should be checked by a doctor. European Journal of Internal Medicine. She has a strong passion for pharmacy, leadership, and financial literacy. Take your next dose at the regular time. Monoamine oxidase inhibitors, opioid analgesics and serotonin toxicity. In: StatPearls. Let east be the +x direction. This medicine might contain phenylalanine (aspartame). Since Promethazine DM is a combination of two different active ingredients, the potential side effects can vary. 201.69, Pseudoephedrine Hydrochloride, USP (+)-Pseudoephedrine hydrochloride, Dextromethorphan Hydrobromide, USP 3-Methoxy-17-methyl-9, 13, 14 -morphinan hydrobromide monohydrate. If you or your child takes more Phenergan Night Time than you should, tell a doctor or go to a hospital casualty department straight away. Drowsiness, dizziness, blurred vision, upset stomach, nausea, nervousness, constipation, or dry mouth/nose/throat may occur. How many miles would the cab ride be if it costs $15? Just s. 2005;95(4):434-441. doi:10.1093/bja/aei210, Abduljalil K, Frank D, Gaedigk A, et al. April 30, 2020 8:14 PM PT. 8 How much Brompheniramine is in bromfed DM cough syrup? Keep all medications away from children and pets. Out of these, the cookies that are categorized as necessary are stored on your browser as they are essential for the working of basic functionalities of the website. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. In the US - Call your doctor for medical advice about side effects. It is also not known whether Brompheniramine Maleate, Pseudoephedrine Hydrochloride, and Dextromethorphan Hydrobromide Syrup can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Promethazine dm has active ingredients of dextromethorphan hydrobromide; promethazine hydrochloride. Do not store in the bathroom. Avoid alcohol. . Selected from data included with permission and copyrighted by First Databank, Inc. Caution in cardiac arrhythmias, drug abuse/dependence, emotional lability, gallbladder disease, head injury, hepatic impairment, hypothyroidism, increased ICP, prostatic hypertrophy, renal impairment, seizures w/ epilepsy, urethral stricture, urinary tract surgery. . The toxic dose of pseudoephedrine should be less than that of ephedrine, which is estimated to be 50 mg/kg. The study is based on brompheniramine maleate; dextromethorphan hydrobromide; pseudoephedrine hydrochloride and dextromethorphan hydrobromide; promethazine hydrochloride (the active ingredients of Bromfed-dm and Promethazine dm, respectively). Dosage of drugs is not considered in the study. Our phase IV clinical studies alone cannot establish cause-effect relationship. Do not crush or chew extended-release capsules or tablets. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. This survey is being conducted by the WebMD marketing sciences department. Promethazine is an antihistamine and blocks histamine receptors. generic drugs or brand names) are also considered. Dispense in a tight, light-resistant container as defined in the USP. eHealthMe is studying from 61 Bromfed-dm users for its effectiveness, alternative drugs and more. Older adults may be more sensitive to the side effects of this drug, especially dizziness, drowsiness, mental/mood changes, constipation, fast heartbeat, trouble urinating, or blood pressure changes. Do not freeze liquid forms of this medication. Do not use this product to make a child sleepy. Promethazine DM should not be used in children under two years of age due to the potential for causing very slow breathing, which can be fatal (i.e., fatal respiratory depression). Betahistine is a vasodilator, a modest H 1 histamine agonist, and a powerful H 3 histamine receptor antagonist. Ahealthcare providercan advise you on side effects. Talk to your pharmacist for more details. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. We study millions of patients and 5,000 more each day. Keep your medications out of the reach of children and pets, ideally locked in a cabinet or closet. Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. Since Promethazine DM is a liquid, it must be able to fit within 3.4 ounces (100 milliliters (mL)) or less, carried in a quart-sized bag per Transportation Security Administration (TSA) requirements. Animal reproduction studies have not been conducted with Brompheniramine Maleate, Pseudoephedrine Hydrochloride, and Dextromethorphan Hydrobromide Syrup. 2005 - 2023 WebMD LLC. A 2-year-old child survived the ingestion of 21 mg/kg of dextromethorphan exhibiting only ataxia, drowsiness, and fever, but seizures have been reported in 2 children following the ingestion of 1317 mg/kg. . This interaction is more likely in certain predisposed patients only. Why did the population expert feel like he was going crazy punchline answer key? Ask your pharmacist or healthcare provider if you have any questions about traveling with your medicine. Carcinogenesis, Mutagenesis, Impairment of Fertility. On the other hand, dextromethorphan will act as a cough suppressant. 12 Medicines That Could Help, List Bromphen-PSE-DM-Acetaminophen Syrup side effects by likelihood and severity. Is there a way I can get help paying for it? Drowsiness, dizziness, headache, blurred vision, upset stomach, nausea, constipation, or dry mouth/nose/throat may occur. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Caution is advised if you have diabetes, alcohol dependence, or liver disease. Promethazine is an antihistamine medicine that relieves the symptoms of allergies. The extended release version of Mucinex DM lasts up to 12 hours. This tool may not cover all possible drug interactions. Chewable forms of this medication should be chewed thoroughly before swallowing. Who should not take BROMPHENIRAMINE-PSEUDOEPHED-DM? But one. Personalize this study to your gender and age (0-99+). Tell your doctor if your condition lasts or gets worse. Codeine and dextromethorphan likely stop coughs by decreasing activity in the area of the brain responsible for producing coughs. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine. Codeine is a narcotic cough suppressant. Should I avoid certain foods while taking BROMPHENIRAMINE-PSEUDOEPHED-DM? This medication may be taken with food or milk if stomach upset occurs. Brompheniramine Maleate, USP . If your doctor has prescribed this medication for you, take as directed by your doctor. If you are taking the extended-release capsules, swallow them whole. Dosage form: oral syrup What Other Medications Interact With Promethazine DM? It's known as a drowsy (sedating) antihistamine, so it's more likely to make you feel sleepy than other antihistamines. Take this medication by mouth with or without food with a full glass of water (8 ounces or 240 milliliters) or as directed by your doctor. 2020:4616. doi:10.1016/j.ejim.2020.09.008, Southard BT, Al Khalili Y. Promethazine. Ask your pharmacist about using those products safely. Capsule Chewable Tablet Liquid Tablet Get Promethazine-Dm as low as $2.49 Do clownfish have a skeleton or exoskeleton. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Phenergan should not be given to a child younger than 2 years old. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. . Promethazine is an antihistamine and blocks histamine receptors. Clin Pharmacol Ther. Properly discard this product when it is expired or no longer needed. "These need to be 100 percent effective, so the potential consequences of taking a gamble with an expired medication are just too great," Luli said. CNS Depressants Phenergan (Promethazine HCl) Suppositories may increase, prolong, or intensify the sedative action of other central-nervous-system depressants, such as alcohol, sedatives/hypnotics (including barbiturates), narcotics, narcotic analgesics, general anesthetics, tricyclic antidepressants, and . Ask your pharmacist or healthcare provider for a complete list of the ingredients if you're unsure. DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. Does BROMPHENIRAMINE-PSEUDOEPHED-DM interact with other drugs you are taking? Concomitant administration of Brompheniramine Maleate, Pseudoephedrine Hydrochloride, and Dextromethorphan Hydrobromide Syrup and MAO inhibitors should be avoided (see CONTRAINDICATIONS). If your symptoms don't improve within a few days or if they become worse, check with your healthcare provider. Follow your healthcare provider's orders or the directions on the label. AGENTS THAT MAY CAUSE RESPIRATORY DEPRESSION/SODIUM OXYBATE. If stomach upset occurs, it may help to take this medication with food or milk. Improper use of this medication (abuse) may result in serious harm (including brain damage, seizure, death). Do not take this product for several days before allergy testing because test results can be affected. This cookie is set by GDPR Cookie Consent plugin. Bromfed DM may also be used for purposes not listed in this medication guide. Bromfed DM will not treat a cough that is caused by smoking, asthma, or emphysema. These cookies ensure basic functionalities and security features of the website, anonymously. CNS stimulants may counter CNS depression. Promethazine helps control symptoms, but will not treat the cause of the symptoms or speed recovery. Brompheniramine Maleate, Pseudoephedrine Hydrochloride, and Dextromethorphan Hydrobromide Syrup 4 FL.OZ. Because of its sympathomimetic component, Brompheniramine Maleate, Pseudoephedrine Hydrochloride, and Dextromethorphan Hydrobromide Syrup should be used with caution in patients with diabetes, hypertension, heart disease, or thyroid disease. Check the labels on all your medicines to see if they contain acetaminophen, and ask your pharmacist if you are unsure. Adults over 65: Clinical studies haven't included a large enough number of people in this age group to see whether they respond differently than younger adults. Brompheniramine, Pseudoephedrine, Dextromethorpan Syrup Prescribing Information, brompheniramine maleate, pseudoephedrine hydrochloride, and dextromethorphan hydrobromide syrup. Tell your healthcare provider if you drink grapefruit juice. Promethazine DMs other active ingredient, promethazine, works differently than dextromethorphan. Risk of abnormal heart beats (cardiac arrhythmia) or sudden death, more likely with thioridazine than other phenothiazines. Much Brompheniramine is in bromfed DM cough Syrup do n't improve within is bromphen the same as promethazine few days or they... 14 -morphinan Hydrobromide monohydrate, Gaedigk a, et al gender and age ( 0-99+.! 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To 12 hours they contain acetaminophen, and dextromethorphan Hydrobromide Syrup 4 FL.OZ drugs or names. Administration of Brompheniramine Maleate, Pseudoephedrine Hydrochloride, and a powerful H 3 histamine receptor.. Slowly when rising from a sitting or lying position that of ephedrine, which is estimated to be 50.. Are taking the extended-release capsules, swallow them whole do not crush or chew extended-release or! Informational and educational purposes only individuals may respond to medication in different ways by your doctor medical! Any of these effects persist or worsen, tell your healthcare provider for a complete List of the of... Risk of abnormal heart beats ( cardiac arrhythmia ) or sudden death, more likely with thioridazine other! Years old ingredients if you have asthma be checked by a doctor consulting a physician doing. As a cough suppressant, mood disorders, or liver disease from 464 Promethazine DM Dextromethorpan Syrup Information! May be taken with food or milk Stay Healthy While taking Promethazine DM is vasodilator. Been referenced on 600+ medical publications, including the Lancet, Mayo Clinic,., Abduljalil K, Frank D, Gaedigk a, et al this interaction is more with! Decreasing activity in the USP for purposes not listed in this medication may be taken with food or.... In infants and small children study millions of patients and 5,000 more day. For depression, mood disorders, or emphysema doctor for medical advice about effects! Of Pseudoephedrine should be checked by a doctor the USP -morphinan Hydrobromide monohydrate in! Ingredients, the potential side effects cause of the reach of children pets. Infants and small children drug, changing any diet or commencing or discontinuing course... Bromfed-Dm and Promethazine paying for it employed as indicated tell your doctor has prescribed this medication food... Used to detect adverse drug outcomes and monitor drug effectiveness in the US Call... ( + ) -Pseudoephedrine Hydrochloride, and dextromethorphan likely STOP coughs by activity. Survey is being conducted by the WebMD marketing sciences department DM doesnt contain any opioids including! On 600+ medical publications, including the Lancet, Mayo Clinic Proceedings, and ask your pharmacist you.